Scientist II, Formulation
Summary To support the growth of the Vaccine & Oncology Platforms, Celsion is seeking to hire a Scientist II, Formulation at its Huntsville, AL, facility to play an integral role in developing novel nucleic acid delivery formulations. About Celsion Celsion Corporation is a fully integrated biopharmaceutical company focused on developing a portfolio of innovative treatments for cancer and infectious diseases using our DNA-mediated gene transfer technologies. Our lead product is GEN-1, a DNA-mediated immunotherapy for the localized treatment of ovarian cancer. Our newest program in development is a novel plasmid DNA-based, investigational vaccine for preventing or treating infections from a broad range of infectious agents including the coronavirus disease using our PLACCINE DNA vaccine technology platform. Duties and responsibilities The successful candidate will:
Produce and characterize novel DNA formulations based on proprietary polymer and lipid based nano delivery systems using appropriate techniques including preparation of nanoparticles, agarose gel electrophoresis, DLS, and other relevant techniques. Conduct experiments to evaluate cell transfection activity and stability characteristics of the formulations to advance scientific understanding of the formulated systems and achieving respective project objectives. Perform quality control testing of the established formulations and coordinate their in vivo testing with Company's project teams and external research collaborators. Have demonstrated the ability to work independently to develop formulations, optimize and troubleshoot the process. Be extremely detail-oriented and place high value in documentation of work for communication to supervisor, other team members and sound development of documentation practices. Effectively communicate with technical and business-oriented audiences within the company through presentations and written reports. Qualifications To be successful in this role your background and experience should include:
S. with 10
years, M.S. with 5
years or Ph.D. with 1-3 years industry experience in nucleic acid formulations. Hands-on experience in DNA or RNA formulation and understanding of the relevant research area are the key metrics for successful selection. Experience in nano-assembly of DNA or RNA drugs into nano-complexes or nano-encapsulates and analytical techniques for particle size, zeta potential and other particle properties. Experience in cell-based assays, standard tissue culture techniques, immunofluorescence, and ELISA will be considered favorably. Good presentation and communication skills and have the ability to identify and apply the appropriate methodologies and data evaluation. Candidate should be familiar with searching and interpreting relevant literature and be able to develop a focused research effort. Must be able to interact with multifunctional personnel and effectively participate in a team environment. Working knowledge of Microsoft Office software, particularly Word and Excel required Excellent interpersonal, organizational and communication skills (oral and written). Ability to prioritize responsibilities, multi-task and remain flexible with changing needs. Ability to handle the pressure of meeting tight deadlines and dynamic work conditions. Ability to work independently as well as with team members. Celsion offers:
Health and Dental insurance, matching 401k, and generous PTO for eligible employees.
Salary Range:
$100K -- $150K
Minimum Qualification
Life SciencesEstimated Salary: $20 to $28 per hour based on qualifications.
Produce and characterize novel DNA formulations based on proprietary polymer and lipid based nano delivery systems using appropriate techniques including preparation of nanoparticles, agarose gel electrophoresis, DLS, and other relevant techniques. Conduct experiments to evaluate cell transfection activity and stability characteristics of the formulations to advance scientific understanding of the formulated systems and achieving respective project objectives. Perform quality control testing of the established formulations and coordinate their in vivo testing with Company's project teams and external research collaborators. Have demonstrated the ability to work independently to develop formulations, optimize and troubleshoot the process. Be extremely detail-oriented and place high value in documentation of work for communication to supervisor, other team members and sound development of documentation practices. Effectively communicate with technical and business-oriented audiences within the company through presentations and written reports. Qualifications To be successful in this role your background and experience should include:
S. with 10
years, M.S. with 5
years or Ph.D. with 1-3 years industry experience in nucleic acid formulations. Hands-on experience in DNA or RNA formulation and understanding of the relevant research area are the key metrics for successful selection. Experience in nano-assembly of DNA or RNA drugs into nano-complexes or nano-encapsulates and analytical techniques for particle size, zeta potential and other particle properties. Experience in cell-based assays, standard tissue culture techniques, immunofluorescence, and ELISA will be considered favorably. Good presentation and communication skills and have the ability to identify and apply the appropriate methodologies and data evaluation. Candidate should be familiar with searching and interpreting relevant literature and be able to develop a focused research effort. Must be able to interact with multifunctional personnel and effectively participate in a team environment. Working knowledge of Microsoft Office software, particularly Word and Excel required Excellent interpersonal, organizational and communication skills (oral and written). Ability to prioritize responsibilities, multi-task and remain flexible with changing needs. Ability to handle the pressure of meeting tight deadlines and dynamic work conditions. Ability to work independently as well as with team members. Celsion offers:
Health and Dental insurance, matching 401k, and generous PTO for eligible employees.
Salary Range:
$100K -- $150K
Minimum Qualification
Life SciencesEstimated Salary: $20 to $28 per hour based on qualifications.
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